Home Print this page Email this page Users Online: 721
Home About us Editorial board Search Ahead of print Current issue Archives Submit article Instructions Subscribe Contacts Login 
ORIGINAL ARTICLE
Year : 2021  |  Volume : 28  |  Issue : 2  |  Page : 31-35

Age-related ultrasonographic mammary gland density patterns: Implication for breast cancer risk


1 Department of Radiation Biology, Radiotherapy and Radiodiagnosis, College of Medicine, University of Lagos, Lagos, Nigeria
2 Department of Anatomy, College of Medicine, University of Lagos, Lagos, Nigeria
3 Department of Biochemistry, College of Medicine, University of Lagos, Lagos, Nigeria
4 Department of Biotechnology, College of Medicine, University of Lagos, Lagos, Nigeria
5 Department of Radiodiagnosis, Lagos University Teaching Hospital, Lagos, Nigeria

Correspondence Address:
Dr. Nicholas Kayode Irurhe
Department of Radiation Biology, Radiotherapy and Radiodiagnosis, College of Medicine, University of Lagos, Lagos
Nigeria
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/wajr.wajr_10_21

Rights and Permissions

Introduction: Mammary gland/breast density is important because it is a known biomarker for breast cancer risk. However, the sensitivity of mammography decreases with high breast density found in younger age group. Ultrasound is considered as the first-line examination in the classification of breast density and in the detection and characterization of breast lesions. This study aims to evaluate the relationship between age and ultrasonographic breast density pattern and its implication for breast cancer risk. Materials and Methods: This was a community-based cross-sectional, exploratory, descriptive study involving 658 females. Breast ultrasonographic scans were performed using a Sonoace X1 Machine with a 7.5 MHz transducer. The lesions detected and classified by ultrasonography as benign or malignant were further subjected to cytopathology. Results: Modal age group of the participants ranged from 33 to 43 years representing 29.8%. There was significant correlation (P<0.01) between ultrasonographic mammary gland density pattern and age, the age group of <33 years demonstrated predominant fibroglandular density pattern with mostly benign lesions, while the age group of 33–53 years demonstrated predominant heterogeneous breast density pattern with most of the malignant lesions in this age group, making it the high-risk group for breast cancer. Conclusion: The relationship between age and ultrasonographic breast density is inversely proportional and not absolute. It also concludes that ultrasonography is a reliable screening tool in the diagnostic process for mammary gland lesions, and as an imaging tool, it is the preferred modality in dense breast. The heterogeneous fibroglandular pattern emerged as the high-risk group for breast cancer, especially in middle age.


[FULL TEXT] [PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed1729    
    Printed70    
    Emailed0    
    PDF Downloaded17    
    Comments [Add]    

Recommend this journal